Small Angle Neutron Scattering - BIO-SANS

Overview

Bio-SANS users are focused on Biology and biomaterials.

Data Reduction Process

They currently use jupyter scripts. Mantid is another way to do the reduction. The staff at ORNL use DRT-SANS to reduce the data.

Data Reduction Software

BIO-SANS Data Reduction Software Links

Software	Description	Documentation	User Guide	Source Code	Paper	Coding Language/ Technologies
Mantid	“The Mantid project provides a framework that supports high-performance computing and visualization of scientific data. Mantid has been created to manipulate and analyze Neutron and Muon scattering data but could be applied to many other techniques” (Mantid Contributors).	Website	Docs	GitHub	Paper	C++ and Python
drtSANS	“Instrument scientists can calibrate instruments and reduce large quantities of datasets. Users can correct the collected data with dark current subtraction and normalization by neutron flux, detector sensitivity, solid angle subtended by the detectors, and scaling to absolute units” (drt-sans Contributors).	Read the docs	–	Code	Paper	Python

Data Analysis Process

A large proportion of users are dependent on the instrument scientists to do the analysis for them. There are a lot of software that can be used. A few examples are ATSAS, BioXTAS RAW, SasView, and Igor. ATSAS is a biological databank. BIOXTAS RAW can do Guinier analysis. SasView is used for shape-dependent analysis. Igor has a higher learning curve but is well-established in the field.

Data Analysis Software

BIO-SANS Data Analysis Software Links

Software	Description	Documentation	User Guide	Source Code	Paper	Coding Language/ Technologies
ATSAS	“The ATSAS software suite encompasses a number of programs for the processing, visualization, analysis and modelling of small-angle scattering data, with a focus on the data measured from biological macromolecules” (ATSAS Paper).	–	Maunals	Website	Paper	–
BIOXTAS RAW	“BioXTAS RAW is a GUI based, free, open-source Python program for reduction and analysis of small-angle X-ray solution scattering (SAXS) data. The software is designed for biological SAXS data” (BioXTAS RAW Contributors).	Read the docs	Tutorial	GitHub	Paper	Python
SasView	“The aim of the SasView project is to provide open source, collaboratively developed software for the analysis of any small angle scattering data” (SasView Contributors).	Website	Tutorial	GitHub	–	Python
IRENA (IgorPro)	“IgorPro is an interactive software environment for experimentation with scientific and engineering data. Igor provides many analysis capabilities, including curve fitting, peak analysis, signal processing and statistics, and much more” (WaveMetrics).	Website	Read the docs	GitHub	Paper	IgorPro